The Rocky Horror Picture Show
In the end, Frank (Tim Curry) is shot and killed by Riff-Raff (Richard O' Brian) with a laser of pure anti-matter. Rocky (Peter Hinwood) picks up Frank and climbs up the radio antenna in the back of the stage. It collapses and Rocky is killed by falling into the pool. Then Brad (Barry Bostwick), Janet (Susan Sarandon) and Dr. Scott (Jonathan Adams) all flee the house, as it takes off for Transsexual, Transylvania.
Thanks, Justin K!