Good Luck
(1996)

Vincent D'Onofrio is former football player who was blinded in an accident.  Gregory Hines is a paraplegic dentist in a wheel chair (yes, he never dances).

After forming a strange friendship, they decide to enter a white water race in Oregon.  The locals are hesitant to allow them to enter until they prove their worth by winning an improvised football game.

They enter the race and come in dead last!  

Thanks Don P!