After Tucker Max convinces his friends Drew and Dan to change the venue of Dan's bachelor party to a different strip club, various hi jinks ensue in the vein of "after that weekend they would never be the same again."
- Tucker (Matt Czuchry)
After Tucker reveals they only went to the club so he could hook up with a midget stripper, he is dis-invited from Dan's wedding. Later, when he insults the wrong girls, his beer is laced with eye drops which causes him to have explosive diarrhea. Realizing that he had gone too far, Tucker crashes the wedding. He makes a speech how he has done whatever he wanted because he expected Dan to clean up his messes, and thus took him for granted. He apologizes to Dan and his new bride Kristy (Keri Lynn Pratt) and shows that he rented a bouncy castle for the reception (something Dan wanted). Tucker is last seen trying to hook up with a blind girl to complete his "Helen Keller" trilogy.
- Drew (Jesse Bradford)
At the strip club Drew is bitter and spiteful to all the women there due to a bad breakup. He meets a stripper named Lara (Marika Dominczyk) who is not only intrigued by him but able to match his insults. She takes him home to play Halo, and Drew bonds with her son over army men. Later, Lara makes Drew realize that if he continues to hate all women due to the lack of character of his ex-fiancee, he will always be miserable. Drew and Lara have sex, and are last seen at Dan's wedding as a couple. Drew hasn't lost his acid wit, but it is apparent he is now happy for the first time in months.
- Dan (Geoff Stults)
Since Tucker abandoned him (and made him lie to Kristy), Dan gets progressively drunk and thrown out of the strip club due to a misunderstanding. He is later arrested and assaulted by cops. When he learns Tucker's true motives for the trip, he realizes he is tired of Tucker's selfish ways and dis-invites him to the wedding. He gets married to Kristy and accepts Tucker's apology after his speech. Their friendship renewed, Drew and Dan ask about the midget stripper before Tucker goes off to court a blind girl. Dan reacts with shock and some disgust as the girl is his cousin.
Look for cameos by rapper Paul Wall as Grillionaire and the Real-Life Tucker Max as Dan's older brother Jeff.